
The Effects
When circulation is robust, everyday activities feel much easier. Nitric oxide encourages blood vessels to relax, enabling oxygen and nutrients to reach your muscles, brain and heart with greater efficiency. This translates to less fatigue when climbing stairs, consistent focus during work, quicker recovery after physical activity, and deeper, more rejuvenating rest.*
Nitric oxide remains vital around the clock. Your body keeps delivering nutrients and clearing waste nonstop — whether you are working, taking a daily walk, or asleep at night.
According to a published open-label study, one serving of Vascanox HP elevates salivary nitric oxide levels for as long as 24 hours.† Its distinctive multi-pathway formula aids nitric oxide creation, storage and delivery. It boosts daily vitality and supports long-term cardiovascular resilience.
Arterosil HP:
My practice is focused on prevention and I routinely discuss optimizing nitric oxide with my patients. Cardiovascular health cannot be well managed without having optimal endothelial function. When lifestyle interventions alone do not optimize endothelial health then it is useful to add targeted supplement support.
Michael Twyman, MD
Board-Certified Cardiologist
The Molecule That Keeps You Moving
The endothelial glycocalyx (EGX) is a delicate, ultra-thin lining covering the interior of every blood vessel throughout your body. Only recently identified and frequently overlooked, it serves as the foundation for vascular wellness and whole-body vitality.
Scientists only recently identified the endothelial glycocalyx, yet it is now acknowledged as one of the body’s most vital structures for human health.
This microscopic gel-like lining carries out many essential tasks to maintain healthy, supple, and robust blood vessels.
Given its essential role in supporting heart and vascular wellness, protecting the endothelial glycocalyx stands as a core focus of contemporary vascular research.
With all of the emerging research on the importance of the glycocalyx for blood-brain barrier integrity, I use Arterosil HP as an essential foundational component for my work in cognitive health.
Kristine Burke, MD, ABFM, ABOIM, IFMCP
Member of Calroy's Science and Medical Advisory Board
Nitric Oxide and Your Vascular Well-being
Nitric oxide plays a key role in vascular health by helping blood vessels relax and widen. This supports healthy blood flow and helps maintain normal blood pressure.
One way nitric oxide is produced involves the endothelium, a thin layer of cells that lines blood vessels. The movement of blood flowing through the vessels prompts the endothelium to produce nitric oxide.
Optimal nitric oxide levels are known to:
Optimal nitric oxide levels are known to:
- Promote a healthy cardiovascular system*
- Help keep blood pressure within its normal range*
- Boost healthy blood circulation*
Calroy’s exclusive formula supports nitric oxide metabolism through multiple biological pathways.
Nitrate → Nitrite → Nitric Oxide Pathway
This pathway begins with the intake of inorganic nitrate — for example, dietary nitrate found in green leafy vegetables — which gets absorbed into the bloodstream. Circulating nitrate travels to the salivary glands and becomes concentrated in saliva.
When released into the mouth, nitrate in saliva is converted to nitrite by nitrate-reducing bacteria. After swallowing, some nitrite undergoes chemical conversion into nitric oxide in the stomach. The remaining nitrite is turned into nitric oxide by various enzymes following absorption.
Ingredients
Vascanox HP features Noxa24, Calroy’s patented extract blend of fermented black garlic, beetroot, and bilberry, combined with potassium nitrate and fruits and vegetables featuring polyphenols. Together, these bioactives nourish the body’s nitric oxide pathways—supporting healthy circulation, vascular flexibility, and endurance throughout the day.*
Every bottle is produced under Calroy’s Total Quality System, with strict compliance to current Good Manufacturing Practices (cGMP) as defined by the FDA. Batch and test records are maintained throughout manufacturing to ensure the guaranteed quality of the final product.
†As demonstrated in a published open-label study using salivary nitric oxide test strips.
Frequently Asked Questions
Who should consider Vascanox HP?
Who should consider Vascanox HP?
Adults looking to support circulation, stamina, or nitric oxide balance may benefit from Vascanox HP.* Simple, salivary test strips can evaluate your nitric oxide levels. Always consult your healthcare provider if you have medical conditions or take prescription medications.
How soon will I notice results?
How soon will I notice results?
Study participants demonstrated nitric oxide levels stayed elevated for up to 24 hours after a single dose.*† Many people notice changes in energy, mental clarity or stamina within days to weeks.* Salivary nitric oxide test strips can be helpful in assessing nitric oxide levels.
Are there any side effects or interactions?
Are there any side effects or interactions?
If you have specific medical conditions or take prescriptions, we recommend speaking with your healthcare provider before adding any supplement to your routine. VascanoxHP® is generally well tolerated. In most cases, it can be taken alongside other supplements or medications.
Can Vascanox HP be taken with Arterosil HP?
Can Vascanox HP be taken with Arterosil HP?
Yes. Each of these supplements supports a different part of the vascular system. Arterosil HP helps support the endothelial glycocalyx, while Vascanox HP supports nitric oxide for optimal circulation.* Used together, they complement one another for comprehensive vascular support.


